ABSTRACT
Current knowledge about the COVID-19 pandemic is still limited, especially in the pediatric age group. So far, children are considered to be a minimally affected population;however, physicians from different parts of the world have recognized a new pediatric multi-systemic inflammatory syndrome, that provokes a multiple organ dysfunction, from which the heart is not exempted. The direct action of the virus on myocardial cells, as well as the cytokines storm -triggered by the infection- are responsible for the myocarditis developed in these patients. In this article a case with criteria of myocarditis associated with COVID-19 is described. Achieving an early diagnosis ofmyocarditis secondary to SARS-CoV-2 infection in the current epidemiological context allows a correct and timely therapeutic approach, avoiding the torpid evolution and fatal outcome of this disease, as well as other long-term complications.
ABSTRACT
Covid-19 has made many universities turn to virtual education, although they do not have it conceived within their educational model. The objective of this research is to evaluate the results achieved in the virtual course of Infotechnology of the Master in Management, of the University of Granma, taught in times of pandemic. A quantitative approach was used, an exploratory-descriptive investigation, with a non-experimental design. The sample consisted of 24 students. The main results highlight an adequate technological scenario that allows you to connect and carry out your investigative activities. 95.83% of the subjects report having received support from the facilitators from a technical and academic point of view. The Chi square test confirms that the quality of the course positively influences the level of acquisition of new knowledge and skills in the search and management of information, by students. It is concluded that the study developed allowed to show the effectiveness of the course in the presence of the health situation, being able to determine that it is feasible to continue with the online training actions of the master’s degree. © 2022, University of Cienfuegos, Carlos Rafael Rodriguez. All rights reserved.
ABSTRACT
OBJECTIVES: To gather, synthesize, and meta-analyze data regarding the risk factors associated with a severe course of COVID-19 among patients with multiple sclerosis (pwMS). METHODS: MEDLINE, Embase, Scopus, and WoS were searched in May 2021. Briefly, the eligibility criteria included: 1) studies assessing COVID-19 severity among adult pwMS; 2) definitive diagnoses or high clinical suspicion of COVID-19; 3) a categorization of COVID-19 severity into at least two categories; 4) quantitative effect size and precision measurements; and 5) English language; and 6) clear effect size/precision measures. internal validity of studies was assessed using the NIH Quality Assessment Tools. A list of possible risk factors was created based on the search results and was later used in extraction, synthesis, and meta-analysis of the data. RESULTS: Thirteen studies were included in the syntheses. Outcome measures were either extracted from the papers, obtained from the primary researchers or calculated manually. The meta-analyses showed a significantly (P<0.05) increased odds of a severe COVID-19 in pwMS with all of the assessed risk factors, except smoking and most DMTs. CONCLUSION: This study facilitates evidence-based risk/benefit assessments in practice. Older men with progressive MS on anti-CD20 therapies are more at risk of an unfortunate COVID-19 outcome.